Side-by-side cost of living comparison for 2026
30% cheaper
St. Louis is 30% more affordable than Naples. A $75,000 salary in Naples is equivalent to $52,734 in St. Louis.
Index values shown. National average = 100. Lower is cheaper.
To maintain the same standard of living:
See exact take-home pay: Florida salaries · Missouri salaries
Housing is typically the biggest factor in any cost-of-living comparison. Naples has a housing index of 180 while St. Louis sits at 72 (national average = 100). The median home in Naples costs $520,000 compared to $175,000 in St. Louis, a difference of $345,000. Monthly rent follows a similar pattern: $2,100 in Naples versus $1,000 in St. Louis.
Groceries and everyday expenses show a notable difference: Naples scores 106 while St. Louis scores 97.
Healthcare costs in Naples (98) are higher than St. Louis (95). Both are close to the national average.
Median household income in Naples is $72,178 compared to $45,782 in St. Louis. When adjusted for cost of living, income goes further in St. Louis.
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