Side-by-side cost of living comparison for 2026
Louisville and Syracuse have very similar costs of living, with less than a 3% difference overall.
Index values shown. National average = 100. Lower is cheaper.
To maintain the same standard of living:
See exact take-home pay: Kentucky salaries ยท New York salaries
Housing is typically the biggest factor in any cost-of-living comparison. Louisville has a housing index of 77 while Syracuse sits at 69 (national average = 100). The median home in Louisville costs $210,000 compared to $140,000 in Syracuse, a difference of $70,000. Monthly rent follows a similar pattern: $1,100 in Louisville versus $950 in Syracuse.
Groceries and everyday expenses show a notable difference: Louisville scores 96 while Syracuse scores 101. Both cities are close to the national average for grocery costs.
Healthcare costs in Louisville (93) are lower than Syracuse (100). Both are close to the national average.
Median household income in Louisville is $52,238 compared to $36,708 in Syracuse. When adjusted for cost of living, purchasing power is similar in both cities.
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