Knoxville vs St. Louis

Category-by-Category Breakdown

Index values shown. National average = 100. Lower is cheaper.

💰 Salary Equivalence

To maintain the same standard of living:

See exact take-home pay: Tennessee salaries · Missouri salaries

Living in Knoxville vs St. Louis

Housing is typically the biggest factor in any cost-of-living comparison. Knoxville has a housing index of 73 while St. Louis sits at 72 (national average = 100). The median home in Knoxville costs $240,000 compared to $175,000 in St. Louis, a difference of $65,000. Monthly rent follows a similar pattern: $1,100 in Knoxville versus $1,000 in St. Louis.

Groceries and everyday expenses show a narrower gap: Knoxville scores 94 while St. Louis scores 97.

Healthcare costs in Knoxville (93) are lower than St. Louis (95). Both are close to the national average.

Median household income in Knoxville is $42,898 compared to $45,782 in St. Louis. When adjusted for cost of living, purchasing power is similar in both cities.

Relocating: Knoxville vs St. Louis

If you are considering a move between Knoxville (index: 88) and St. Louis (index: 90), the 2% cost difference has real implications for your budget. Knoxville is the more affordable option, but the right choice depends on your income, career opportunities, and lifestyle priorities.

Housing budget reality: Using the 28% rule (spending no more than 28% of gross income on housing), the median household in Knoxville can afford $1,001/month, while the median household in St. Louis can afford $1,068/month. With median homes at $240,000 in Knoxville versus $175,000 in St. Louis, both cities offer reasonable homeownership opportunities at median income.

Renting vs buying: At $1,100/month in Knoxville and $1,000/month in St. Louis, renters face similar costs in both cities. The rent-to-own ratio in each city determines whether renting or buying offers better value for your situation.

Income adjustment: A $75,000 salary goes further in Knoxville where costs are 12% below the national average. Before accepting a job in either city, use the salary equivalence data above to understand what you would need to earn to maintain your current standard of living.

Reading These Numbers: Knoxville (88) vs St. Louis (90)

The cost of living index uses 100 as the national average. Knoxville at 88 is 12% below the US average, while St. Louis at 90 is 10% below average. Both cities are relatively affordable compared to the national average.

The overall index is a weighted average of housing (the largest component), groceries, utilities, transportation, and healthcare. Housing typically drives the biggest differences between cities. Even when two cities have similar overall indices, their category-level costs can vary significantly — one city might have expensive housing but cheap groceries, while another is the reverse. Check the category breakdown above for the full picture.

For renters: With median rents of $1,100/month in Knoxville and $1,000/month in St. Louis, the annual rent difference is approximately $1,200. Over a 5-year period, that compounds to $6,000 in savings by choosing the more affordable city.

For homebuyers: The $65,000 difference in median home prices between Knoxville and St. Louis translates to roughly $3,900 per month in mortgage payments at current rates. Factor this into your budget alongside property taxes and insurance, which also vary by location.

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