Greenville vs Sioux Falls
Side-by-side cost of living comparison for 2026
Greenville
Sioux Falls
๐ก The Verdict
Greenville and Sioux Falls have very similar costs of living, with less than a 3% difference overall.
Category-by-Category Breakdown
Index values shown. National average = 100. Lower is cheaper.
๐ฐ Salary Equivalence
To maintain the same standard of living:
See exact take-home pay: South Carolina salaries ยท South Dakota salaries
Living in Greenville vs Sioux Falls
Housing is typically the biggest factor in any cost-of-living comparison. Greenville has a housing index of 85 while Sioux Falls sits at 80 (national average = 100). The median home in Greenville costs $250,000 compared to $265,000 in Sioux Falls, a difference of $15,000. Monthly rent follows a similar pattern: $1,200 in Greenville versus $1,100 in Sioux Falls.
Groceries and everyday expenses show a narrower gap: Greenville scores 98 while Sioux Falls scores 97. Both cities are close to the national average for grocery costs.
Healthcare costs in Greenville (103) are higher than Sioux Falls (101). Both are close to the national average.
Median household income in Greenville is $48,912 compared to $61,714 in Sioux Falls. When adjusted for cost of living, purchasing power is similar in both cities.
Relocating: Greenville vs Sioux Falls
If you are considering a move between Greenville (index: 95) and Sioux Falls (index: 93), the 2% cost difference has real implications for your budget. Sioux Falls is the more affordable option, but the right choice depends on your income, career opportunities, and lifestyle priorities.
Housing budget reality: Using the 28% rule (spending no more than 28% of gross income on housing), the median household in Greenville can afford $1,141/month, while the median household in Sioux Falls can afford $1,440/month. With median homes at $250,000 in Greenville versus $265,000 in Sioux Falls, both cities offer reasonable homeownership opportunities at median income.
Renting vs buying: At $1,200/month in Greenville and $1,100/month in Sioux Falls, renters face similar costs in both cities. The rent-to-own ratio in each city determines whether renting or buying offers better value for your situation.
Income adjustment: A $75,000 salary goes further in Sioux Falls where costs are 7% below the national average. Before accepting a job in either city, use the salary equivalence data above to understand what you would need to earn to maintain your current standard of living.
Reading These Numbers: Greenville (95) vs Sioux Falls (93)
The cost of living index uses 100 as the national average. Greenville at 95 is 5% below the US average, while Sioux Falls at 93 is 7% below average. Both cities are close to the national average in overall costs.
The overall index is a weighted average of housing (the largest component), groceries, utilities, transportation, and healthcare. Housing typically drives the biggest differences between cities. Even when two cities have similar overall indices, their category-level costs can vary significantly โ one city might have expensive housing but cheap groceries, while another is the reverse. Check the category breakdown above for the full picture.
For renters: With median rents of $1,200/month in Greenville and $1,100/month in Sioux Falls, the annual rent difference is approximately $1,200. Over a 5-year period, that compounds to $6,000 in savings by choosing the more affordable city.
For homebuyers: The $15,000 difference in median home prices between Greenville and Sioux Falls translates to roughly $900 per month in mortgage payments at current rates. Factor this into your budget alongside property taxes and insurance, which also vary by location.
๐ Related Tools
๐ Moving & Relocation Resources
Amazon affiliate links