Side-by-side cost of living comparison for 2026
17% cheaper
Greenville is 17% more affordable than Eugene. A $75,000 salary in Eugene is equivalent to $61,957 in Greenville.
Index values shown. National average = 100. Lower is cheaper.
To maintain the same standard of living:
See exact take-home pay: Oregon salaries · South Carolina salaries
Housing is typically the biggest factor in any cost-of-living comparison. Eugene has a housing index of 130 while Greenville sits at 85 (national average = 100). The median home in Eugene costs $380,000 compared to $250,000 in Greenville, a difference of $130,000. Monthly rent follows a similar pattern: $1,400 in Eugene versus $1,200 in Greenville.
Groceries and everyday expenses show a notable difference: Eugene scores 103 while Greenville scores 98. Both cities are close to the national average for grocery costs.
Healthcare costs in Eugene (106) are higher than Greenville (103). Both are close to the national average.
Median household income in Eugene is $49,448 compared to $48,912 in Greenville. When adjusted for cost of living, income goes further in Greenville.
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