Side-by-side cost of living comparison for 2026
10% cheaper
Louisville is 10% more affordable than Durham. A $75,000 salary in Durham is equivalent to $67,574 in Louisville.
Index values shown. National average = 100. Lower is cheaper.
To maintain the same standard of living:
See exact take-home pay: North Carolina salaries · Kentucky salaries
Housing is typically the biggest factor in any cost-of-living comparison. Durham has a housing index of 104 while Louisville sits at 77 (national average = 100). The median home in Durham costs $340,000 compared to $210,000 in Louisville, a difference of $130,000. Monthly rent follows a similar pattern: $1,400 in Durham versus $1,100 in Louisville.
Groceries and everyday expenses show a narrower gap: Durham scores 100 while Louisville scores 96. Both cities are close to the national average for grocery costs.
Healthcare costs in Durham (108) are higher than Louisville (93).
Median household income in Durham is $57,738 compared to $52,238 in Louisville. When adjusted for cost of living, income goes further in Louisville.
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