Durham vs Knoxville
Side-by-side cost of living comparison for 2026
Durham
Knoxville
๐ก The Verdict
13% cheaper
Knoxville is 13% more affordable than Durham. A $75,000 salary in Durham is equivalent to $65,347 in Knoxville.
Category-by-Category Breakdown
Index values shown. National average = 100. Lower is cheaper.
๐ฐ Salary Equivalence
To maintain the same standard of living:
See exact take-home pay: North Carolina salaries ยท Tennessee salaries
Living in Durham vs Knoxville
Housing is typically the biggest factor in any cost-of-living comparison. Durham has a housing index of 104 while Knoxville sits at 73 (national average = 100). The median home in Durham costs $340,000 compared to $240,000 in Knoxville, a difference of $100,000. Monthly rent follows a similar pattern: $1,400 in Durham versus $1,100 in Knoxville.
Groceries and everyday expenses show a notable difference: Durham scores 100 while Knoxville scores 94.
Healthcare costs in Durham (108) are higher than Knoxville (93).
Median household income in Durham is $57,738 compared to $42,898 in Knoxville. When adjusted for cost of living, income goes further in Knoxville.
Relocating: Durham vs Knoxville
If you are considering a move between Durham (index: 101) and Knoxville (index: 88), the 13% cost difference has real implications for your budget. Knoxville is the more affordable option, but the right choice depends on your income, career opportunities, and lifestyle priorities.
Housing budget reality: Using the 28% rule (spending no more than 28% of gross income on housing), the median household in Durham can afford $1,347/month, while the median household in Knoxville can afford $1,001/month. With median homes at $340,000 in Durham versus $240,000 in Knoxville, both cities offer reasonable homeownership opportunities at median income.
Renting vs buying: At $1,400/month in Durham and $1,100/month in Knoxville, renters face similar costs in both cities. The rent-to-own ratio in each city determines whether renting or buying offers better value for your situation.
Income adjustment: A $75,000 salary goes further in Knoxville where costs are 12% below the national average. Before accepting a job in either city, use the salary equivalence data above to understand what you would need to earn to maintain your current standard of living.
Reading These Numbers: Durham (101) vs Knoxville (88)
The cost of living index uses 100 as the national average. Durham at 101 is 1% above the US average, while Knoxville at 88 is 12% below average. There is a meaningful cost gap between these two cities that affects day-to-day budgeting.
The overall index is a weighted average of housing (the largest component), groceries, utilities, transportation, and healthcare. Housing typically drives the biggest differences between cities. Even when two cities have similar overall indices, their category-level costs can vary significantly โ one city might have expensive housing but cheap groceries, while another is the reverse. Check the category breakdown above for the full picture.
For renters: With median rents of $1,400/month in Durham and $1,100/month in Knoxville, the annual rent difference is approximately $3,600. Over a 5-year period, that compounds to $18,000 in savings by choosing the more affordable city.
For homebuyers: The $100,000 difference in median home prices between Durham and Knoxville translates to roughly $6,000 per month in mortgage payments at current rates. Factor this into your budget alongside property taxes and insurance, which also vary by location.
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