Side-by-side cost of living comparison for 2026
9% cheaper
Indianapolis is 9% more affordable than Durham. A $75,000 salary in Durham is equivalent to $68,317 in Indianapolis.
Index values shown. National average = 100. Lower is cheaper.
To maintain the same standard of living:
See exact take-home pay: North Carolina salaries · Indiana salaries
Housing is typically the biggest factor in any cost-of-living comparison. Durham has a housing index of 104 while Indianapolis sits at 80 (national average = 100). The median home in Durham costs $340,000 compared to $220,000 in Indianapolis, a difference of $120,000. Monthly rent follows a similar pattern: $1,400 in Durham versus $1,100 in Indianapolis.
Groceries and everyday expenses show a narrower gap: Durham scores 100 while Indianapolis scores 98. Both cities are close to the national average for grocery costs.
Healthcare costs in Durham (108) are higher than Indianapolis (96).
Median household income in Durham is $57,738 compared to $49,968 in Indianapolis. When adjusted for cost of living, income goes further in Indianapolis.
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