๐Ÿ“Š Cost of Living Comparison

Des Moines vs Santa Fe

Side-by-side cost of living comparison for 2026

Des Moines

Iowa
89
Below Average
$210,000
Median Home
$1,100/mo
Median Rent
$55,958
Median Income

Santa Fe

New Mexico
117
Above Average
$480,000
Median Home
$1,600/mo
Median Rent
$61,982
Median Income

๐Ÿ’ก The Verdict

24% cheaper
Des Moines is 24% more affordable than Santa Fe. A $75,000 salary in Santa Fe is equivalent to $57,051 in Des Moines.

Category-by-Category Breakdown

Index values shown. National average = 100. Lower is cheaper.

Housing
74
Des Moines
153
Santa Fe
Groceries
96
Des Moines
103
Santa Fe
Utilities
93
Des Moines
96
Santa Fe
Transportation
100
Des Moines
99
Santa Fe
Healthcare
97
Des Moines
95
Santa Fe

๐Ÿ’ฐ Salary Equivalence

To maintain the same standard of living:

$98,596
$75K in Des Moines โ†’ Santa Fe
$57,051
$75K in Santa Fe โ†’ Des Moines

See exact take-home pay: Iowa salaries ยท New Mexico salaries

Living in Des Moines vs Santa Fe

Housing is typically the biggest factor in any cost-of-living comparison. Des Moines has a housing index of 74 while Santa Fe sits at 153 (national average = 100). The median home in Des Moines costs $210,000 compared to $480,000 in Santa Fe, a difference of $270,000. Monthly rent follows a similar pattern: $1,100 in Des Moines versus $1,600 in Santa Fe.

Groceries and everyday expenses show a notable difference: Des Moines scores 96 while Santa Fe scores 103. Both cities are close to the national average for grocery costs.

Healthcare costs in Des Moines (97) are higher than Santa Fe (95). Both are close to the national average.

Median household income in Des Moines is $55,958 compared to $61,982 in Santa Fe. When adjusted for cost of living, income goes further in Des Moines.

Relocating: Des Moines vs Santa Fe

If you are considering a move between Des Moines (index: 89) and Santa Fe (index: 117), the 24% cost difference has real implications for your budget. Des Moines is the more affordable option, but the right choice depends on your income, career opportunities, and lifestyle priorities.

Housing budget reality: Using the 28% rule (spending no more than 28% of gross income on housing), the median household in Des Moines can afford $1,306/month, while the median household in Santa Fe can afford $1,446/month. With median homes at $210,000 in Des Moines versus $480,000 in Santa Fe, homeownership requires above-median income in the pricier market.

Renting vs buying: At $1,100/month in Des Moines and $1,600/month in Santa Fe, renters save significantly in Des Moines. The rent-to-own ratio in each city determines whether renting or buying offers better value for your situation.

Income adjustment: A $75,000 salary goes further in Des Moines where costs are 11% below the national average. Before accepting a job in either city, use the salary equivalence data above to understand what you would need to earn to maintain your current standard of living.

Reading These Numbers: Des Moines (89) vs Santa Fe (117)

The cost of living index uses 100 as the national average. Des Moines at 89 is 11% below the US average, while Santa Fe at 117 is 17% above average. There is a meaningful cost gap between these two cities that affects day-to-day budgeting.

The overall index is a weighted average of housing (the largest component), groceries, utilities, transportation, and healthcare. Housing typically drives the biggest differences between cities. Even when two cities have similar overall indices, their category-level costs can vary significantly โ€” one city might have expensive housing but cheap groceries, while another is the reverse. Check the category breakdown above for the full picture.

For renters: With median rents of $1,100/month in Des Moines and $1,600/month in Santa Fe, the annual rent difference is approximately $6,000. Over a 5-year period, that compounds to $30,000 in savings by choosing the more affordable city.

For homebuyers: The $270,000 difference in median home prices between Des Moines and Santa Fe translates to roughly $16,200 per month in mortgage payments at current rates. Factor this into your budget alongside property taxes and insurance, which also vary by location.

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