Side-by-side cost of living comparison for 2026
4% cheaper
Cheyenne is 4% more affordable than Mesa. A $75,000 salary in Mesa is equivalent to $71,970 in Cheyenne.
Index values shown. National average = 100. Lower is cheaper.
To maintain the same standard of living:
See exact take-home pay: Wyoming salaries ยท Arizona salaries
Housing is typically the biggest factor in any cost-of-living comparison. Cheyenne has a housing index of 85 while Mesa sits at 98 (national average = 100). The median home in Cheyenne costs $280,000 compared to $350,000 in Mesa, a difference of $70,000. Monthly rent follows a similar pattern: $1,100 in Cheyenne versus $1,350 in Mesa.
Groceries and everyday expenses show a narrower gap: Cheyenne scores 98 while Mesa scores 99. Both cities are close to the national average for grocery costs.
Healthcare costs in Cheyenne (100) are higher than Mesa (95). Both are close to the national average.
Median household income in Cheyenne is $57,834 compared to $60,234 in Mesa. When adjusted for cost of living, income goes further in Cheyenne.
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