Side-by-side cost of living comparison for 2026
47% cheaper
Greenville is 47% more affordable than Cambridge. A $75,000 salary in Cambridge is equivalent to $40,028 in Greenville.
Index values shown. National average = 100. Lower is cheaper.
To maintain the same standard of living:
See exact take-home pay: Massachusetts salaries · South Carolina salaries
Housing is typically the biggest factor in any cost-of-living comparison. Cambridge has a housing index of 280 while Greenville sits at 85 (national average = 100). The median home in Cambridge costs $890,000 compared to $250,000 in Greenville, a difference of $640,000. Monthly rent follows a similar pattern: $3,100 in Cambridge versus $1,200 in Greenville.
Groceries and everyday expenses show a notable difference: Cambridge scores 110 while Greenville scores 98.
Healthcare costs in Cambridge (118) are higher than Greenville (103).
Median household income in Cambridge is $103,154 compared to $48,912 in Greenville. When adjusted for cost of living, income goes further in Greenville.
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