Side-by-side cost of living comparison for 2026
21% cheaper
St. Louis is 21% more affordable than Ann Arbor. A $75,000 salary in Ann Arbor is equivalent to $59,211 in St. Louis.
Index values shown. National average = 100. Lower is cheaper.
To maintain the same standard of living:
See exact take-home pay: Michigan salaries · Missouri salaries
Housing is typically the biggest factor in any cost-of-living comparison. Ann Arbor has a housing index of 135 while St. Louis sits at 72 (national average = 100). The median home in Ann Arbor costs $400,000 compared to $175,000 in St. Louis, a difference of $225,000. Monthly rent follows a similar pattern: $1,600 in Ann Arbor versus $1,000 in St. Louis.
Groceries and everyday expenses show a narrower gap: Ann Arbor scores 101 while St. Louis scores 97. Both cities are close to the national average for grocery costs.
Healthcare costs in Ann Arbor (101) are higher than St. Louis (95). Both are close to the national average.
Median household income in Ann Arbor is $65,024 compared to $45,782 in St. Louis. When adjusted for cost of living, income goes further in St. Louis.
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